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Growing Threat of NDM-CRE

Post Date: 09/30/2025

Recent reports have shown an increase of more than 400 percent in infections from New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE). In New York City, NDM-positive CRE surpassed Klebsiella pneumonia carbapenemase (KPC)-positive CRE cases in 2024. Providers should be aware of predominant carbapenemases within their clinical settings when initiating antibiotic treatment for patients with CRE infections. Read more from CDC’s MMWR.